The Merseysiders sit atop the league table with 42 points, whereas the 6th-placed Red Devils trail their upcoming opponents by 16 whole points.
Ahead of the exciting clash, Sky Sports pundits Jamie Carragher and Gary Neville, who also happen to be legends of the two clubs, were seen picking the combined XI from the current squads on the Monday Night Football show.
An interesting moment occurred when Neville included United’s out-of-form talisman Paul Pogba as the holding midfielder in his 4-3-3 setup – a decision that was mocked and questioned by Carragher.
“Holding what? He’s the most undisciplined player of all time!” the former centre-back pointed out.
Neville replied with an explanation, admitting: “I didn’t pick him with much conviction, to be honest with you. I was clutching at straws. Matić, Jordan Henderson, and James Milner, they’re in and out of that midfield in terms of playing.
“I wasn’t convinced by anything just through what’s been happening. I just thought it’s an opportunity for me to put a United player in, to be honest!
“Perhaps I was clutching at straws, but I looked at it as an opportunity to put a United player in there, as I think Pogba is United’s best central midfield player and the most talented at the two clubs.”
Carragher decided to go with Pogba’s fellow midfield partner instead, as he explained: “I’ve put Nemanja Matić in because he’s the classic holding midfielder; he’s been there, done it and won titles. He’s probably the best holding midfield player in both squads.”